General Description:
Artesunate 50 mg tablets + Mefloquine 250 mg tablets, co-packed in
blister strips of 6+2 tablets, pack of 1
Technical specifications
Each uncoated tablet of Artesunate contains: Artesunate 50mg (as sodium
salt)
Each uncoated tablet of Mefloquine contains: Mefloquine base 250mg,
equivalent to 274mg Mefloquine hydrochloride salt.
Both tablets should be scored with at least one break line to allow for
division of tablets into two parts, each containing the same amount of
active ingredients.
Therapeutic class
Artesunate is water soluble sodium salt of the hemisuccinate ester of
dihydroartemesinin.
Mefloquine is a 4-methanolquinoline and is related to quinine.
Standard shelf life
2 years (24 months)
Other available formulations
Artesunate 50mg + Mefloquine 250mg co-blistered tablets, Pack of 3+1,
6+2, 9+3, 12+5 tablets
Artesunate 200mg + Mefloquine 250mg co-blistered tablets, Pack of 3+6
tablets
Indications
Treatment of uncomplicated malaria caused by P. falciparum alone or with
other Plasmodium spp. In areas with significant drug resistance: By
Mouth (PO)
Dosage
Suggested dosing is based on the WHO guidelines for the treatment of
Malaria: www.who.int/malaria/publications/atoz/9241546948/en/index.html
Storage
Protect from moisture.
Keep out of the reach and sight of children.
Temperature considerations
Do not store above 25 °C (77 °F).
Dispensing instructions
Dispense in original container. Do not repack
Both Artesunate and Mefloquine must be taken in combination with each
other.
Guidelines for use
For more details, please see
World Health Organisation (WHO), Guidelines for the treatment of
Malaria: (www.who.int/malaria/en/)
WHO, Model Lists of Essential Medicines for adults and/or children
respectively:
(www.who.int/medicines/publications/essentialmedicines/en/index.html)
WHO Model Formulary: (apps.who.int/emlib/Default.aspx?Language=EN)
or your regional and/or national guidelines.
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